Research Groups

Omics of Algae

Research Interests and Description

Group Leader: Pavan Jutur, PhD

Group Members

Research Interests

Integrated Omics, Algal Biotechnology, B3 Algae (Biomass, Biofuels & Bioproducts)

Description of Research

Microalgae, a potential source for next-generation renewable biomass, biofuels, and bioproducts (B3 Algae)
Microalgae hold promising source of renewable energy to replace diminishing oil reserves as a source of lipids for biofuels. Algal Oils are rich in the triacylglycerols (TAGs) that serve as material for conversion to biofuels. Studies on the biosynthetic pathways and rate limiting steps of triacylglycerol formation in microalgae are still infancy. My research aims to study the overall TAG biosynthesis pathway, oil mobilization and role of beta-oxidation genes in TAG catabolism and also RNA-mediated silencing altering the lipid content with increase in overall lipid production or shift the balance of lipid production. Understanding these biosynthetic pathways and the adaptation of systems-based approaches to metabolic engineering of microalgae may be a critical step towards making algae-derived biofuels economically competitive.

Exploring the microalgal systems through integrated omics research
Decreasing fossil fuels and its impact on global warming led to an increasing demand for its replacement by sustainable renewable biofuels. Microalgae may offer a potential feedstock for renewable biofuels capable of converting atmospheric CO2 to substantial biomass and valuable biofuels, which is of great importance for the food and energy industries. Integrated omics research is a powerful tool in understanding the behaviour of biological systems as a whole, where the metabolic pathways are often highly regulated and connected with a number of both feedforward and feedback mechanisms that can act positively and/or negatively ultimately affecting the systems output. Understanding the entire system through integrated omics will lead to identify relevant enzyme-encoding genes, and reconstruct the metabolic pathways involved in the biosynthesis and degradation of precursor molecules that may have potential for biofuel production, aiming towards the vision of tomorrow’s bioenergy needs. 

Recent Publications

Kapase, V.U., Nesamma, A.A., Jutur, P.P. 2018. Identification and characterization of candidates involved in production of OMEGAs in Microalgae: a gene mining and phylogenomics approach. Prep Biochem Biotechnol doi: 10.1080/10826068.2018. 1476886 PubMed link

Ashwani, K.R., Asha, A.N., Jutur, P.P. 2017. Stress Biology in Microalgae Depicts Molecular Insights for Simultaneous Production of Lipids and High Value Precursors. Adv Biotech Micro. 6, 555699, doi: 10.19080/AIBM.2017.06.555699 

Kashif, M.S., Asha, A.N., Abdin, M.Z., Jutur, P.P. 2017. Evaluation of growth and lipid profiles in six different microalgal strains for biofuel production. In: Recent Advances in Bioenergy Research, Proceedings of the Second International Conference. ed. Kumar S, et al. Springer Singapore pp. 3-16 doi: 10.1007/978-981-10-6107-3_1 

Sardar, R., Kashif, M.S., Jutur, P.P. 2016. Identification of transcription hubs that control lipid metabolism and carbon concentrating mechanism in model microalgae Chlamydomonas reinhardtii using regulatory networks. International Conference on Bioinformatics and Systems Biology (BSB), Allahabad, pp. 1-4 doi: 10.1109/BSB.2016.7552116 

Jutur. P.P., Asha, A.N., Kashif, M.S. 2016. Algae-derived marine oligosaccharides and their biological applications. Frontiers in Marine Science 3, 1-5 doi: 10.3389/fmars. 2016.00083 

Asha, A.N., Kashif, M.S., Jutu, P.P. 2016. De novo transcriptomics in marine microalgae: an advanced genetic engineering approach for next-generation renewable biofuels. In: Marine OMICS: Principles and Applications. Ed. Kim, S.K.: CRC Press, 283-296 doi: 10.1201/9781315372303-16 

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